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Monensin

Product Name
Monensin
CAS No.
17090-79-8
Chemical Name
Monensin
Synonyms
MONENSIN SODIUM;a3823a;monelan;MONENSIN;Romensin;elancoban;Monensin A;MONENSIN NA;Monensin 20%;monensicacid
CBNumber
CB9748019
Molecular Formula
C36H62O11
Formula Weight
670.87
MOL File
17090-79-8.mol
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Monensin Property

Melting point:
103-105°C
alpha 
D +47.7°
Boiling point:
608.24°C (rough estimate)
Density 
1.0773 (rough estimate)
refractive index 
1.5465 (estimate)
storage temp. 
2-8°C
pka
6.6 (in 66% DMF)
CAS DataBase Reference
17090-79-8(CAS DataBase Reference)
EPA Substance Registry System
Monensin (17090-79-8)
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
36/37/39-45
WGK Germany 
3
RTECS 
JH2830000
Hazardous Substances Data
17090-79-8(Hazardous Substances Data)
Toxicity
LD50 of monensin complex in mice, chicks (mg/kg): 43.8 ± 5.2, 284 ± 47 orally (Haney, Hoehn)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
M4900-01
Product name
Monensin A
Packaging
5mg
Price
$362
Updated
2021/12/16
Usbiological
Product number
M4435-02
Product name
Monensin
Packaging
500ul
Price
$393
Updated
2021/12/16
Biorbyt Ltd
Product number
orb593405
Product name
Monensin
Packaging
50μg
Price
$425
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008060
Product name
MONENSIN
Purity
95.00%
Packaging
5MG
Price
$497.06
Updated
2021/12/16
Biorbyt Ltd
Product number
orb593405
Product name
Monensin
Packaging
100μg
Price
$635.8
Updated
2021/12/16
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Monensin Chemical Properties,Usage,Production

Description

Monensin was found in the mycelium of Streptomyces cinnamonensis by Eli Lilly & Co. in 1967 in the course of screening for anticoccidial and growth-promoting substances for cattle, swine, and chickens. It shows antiprotozoal, antibacterial, and antifungal activities, as well as anticoccidial activity. Monensin is widely used to treat such infections and as a feed additive to promote the growth of livestock.

Chemical Properties

Crystallin Solid

Uses

Monensin A is a polyether antibiotic first isolated from Streptomyces cinnamonensis in 1967. Monensin A is a broad-spectrum anticoccicidial antibiotic, also exhibiting antifungal and antiviral activity. Monensin A forms complexes with monovalent cations such as Li+, Na+, K+, Rb+, Ag+ and Tl+ and is thus able to transport these cations across lipid membranes of cells, playing an important role as an Na+/H+ antiporter. It blocks intracellular protein transport and is used in animals to prevent coccidiosis, promote growth and prevent bloat. Derivatives of monensin, monensin methyl ester and particularly monensin decyl ester, are used in ion selective electrodes.

Uses

Poliether antibiotic. Coccidiostat

Uses

Monensin (2) C36H62O11, a carboxylic acid which is used as its water-soluble sodium salt (Coban, Rumensin). Monensin is also used to treat histomoniasis. The polyether ionophoric antibiotics are capable of complexing and interfacing with specific alkali metal cations to render them lipid-soluble and diffusible across parasite mitochondrial membranes. Related useful polyether antibiotics are narasin and lasalocid (3, Lasalocid A, C34H54O8,).

Definition

ChEBI: Monensin A is a spiroketal, monensin A is the major component of monensin, a mixture of antibiotic substances produced by Streptomyces cinnamonensis. An antiprotozoal, it is used as the sodium salt as a feed additive for the prevention of coccidiosis in poultry and as a growth promoter in cattle. It has a role as a coccidiostat, an antifungal agent and an ionophore. It is a monocarboxylic acid, a cyclic hemiketal, a spiroketal and a polyether antibiotic.

brand name

Coban [as sodium salt] (Lilly);Rumensin [as sodium salt] (Lilly).

Safety Profile

Poison by ingestion and intraperitoneal routes. An eye and skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Monensin Preparation Products And Raw materials

Raw materials

Preparation Products

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Monensin Suppliers

Canada 1 China 159 Europe 2 France 1 Germany 1 India 5 Japan 2 South Korea 1 Switzerland 2 United Kingdom 9 United States 25 Global 208
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
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View Lastest Price from Monensin manufacturers

Henan Suikang Pharmaceutical Co.,Ltd.
Product
Monensin 17090-79-8
Price
US $0.00/kg
Min. Order
25kg
Purity
99.0%
Supply Ability
10tons
Release date
2024-04-29
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Monensin 17090-79-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-04-07
Henan Fengda Chemical Co., Ltd
Product
Monensin 17090-79-8
Price
US $34.00-1.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-22

17090-79-8, MonensinRelated Search:

Methylparaben Bensulfuron methyl Ivermectin Nystatin CHLOROPHOSPHONAZO III METSULFURON METHYL Methyl salicylate Thiophanate-methyl Kresoxim-methyl Abamectin Methyl Methyl bromide MONENSIN SODIUM SALT HYDRATE,monensin,monosodiumsal Parathion-methyl 16-Deethyl-3-O-demethyl-16-methyl-3-O-(1-oxopropyl)monensin,Monensin, 16-deethyl-3-O-demethyl-16-methyl-3-O-(1-oxopropyl)- monensin B Monensin 26-[N-(2-phenylethyl)carbamate] MONENSIN DECYL ESTER

  • 2-(5-ethyltetrahydro-5-(tetrahydro-3-6-dioxaspiro(4.5)decane-7-butyricacid
  • a3823a
  • elancoban
  • gamma,2,8-tetramethyl--furyl)-2-furyl)-9-hydroxy-beta-methoxy-alph
  • monelan
  • Monensine sodium
  • 4-[2-[2-Ethyl-5-(6-hydroxy-6-hydroxymethyl-3,5-dimethyltetrahydropyran-2-yl)-3-methyloctahydro-[2,2]bifuranyl-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid
  • Monensin A
  • 4-[2-(5-ethyl-5-{5-[6-hydroxy-6-(hydroxyMethyl)-3,5-diMethyloxan-2-yl]-3-Methyloxolan-2-yl}oxolan-2-yl)-9-hydroxy-2,8-diMethyl-1,6-dioxaspiro[4.5]decan-7-yl]-3-Methoxy-2-Methylpentanoic acid
  • Monensin 20%
  • Monensic acid, Lilly 67314, A 3223A.
  • Monensin premix
  • MONENSIN NA
  • MONENSIN SODIUM
  • MONENSIN A SODIUM SALT
  • MONENSIN
  • monensicacid
  • 4-[3-[5-ETHYL-5-[5-[6-HYDROXY-6-(HYDROXYMETHYL)-3,5-DIMETHYL-TETRAHYDROPYRAN-2-YL]-3-METHYL-TETRAHYDROFURAN-2-YL]-TETRAHYDROFURAN-2-YL]-9-HYDROXY-3,8-DIMETHYL-4,6-DIOXASPIRO[4.5]DEC-7-YL]-3-METHOXY-2-METHYL-PENTANOATE
  • 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-beta-methoxy-alpha,gamma,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric acid
  • Romensin
  • 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy--methoxy-a,,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric Acid
  • MONENSIN(PURE)
  • MONENSINSODIUMSALT(30%)
  • Monensin：Monesin Sodium
  • Monensin USP/EP/BP
  • 17090-79-8 Monensin
  • 17090-79-8
  • 2411-54-0
  • C36H61O11Na
  • C36H62O11
  • C37H63NaO10
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API's